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KMID : 0614620160680020099
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Korean Journal of Gastroenterology
2016 Volume.68 No. 2 p.99 ~ p.103
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Gastric Mucormycosis Followed by Traumatic Cardiac Rupture in an Immunocompetent Patient
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Lee Sang-Won
Lee Hyun-Seok
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Abstract
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Gastric mucormycosis is a rare and life-threatening fungal disease, caused by fungus in the order Mucorales. While rhino-cerebral and pulmonary forms are common, gastric mucormycosis is an uncommon site for the disease. We diagnosed gastric mucormycosis in a 41-year-old female who had severe multiple trauma, including cardiac rupture, due to a traffic accident. Eighteen days after hospitalization, she passed 800 mL of melena over one day. We performed upper esophagogastroduodenoscopy (EGD) and found a huge gastric ulcer with bleeding. Histopathological examination identified non-septated and right-angled branching fungal hyphae, and we diagnosed gastric mucormycosis. We recommended total gastrectomy to her but she refused the operation, so she was treated with liposomal amphotericin B for 53 days. After two months of treatment with liposomal amphotericin B, we again performed EGD and found a healed gastric ulcer. After four months, with another EGD, we found that the gastric mucormycosis was completely healed.
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KEYWORD
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Gastric mucormycosis, Immunocompetent, Heart rupture, Amphotericin B
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